articlemSystemsFeb 11, 2019GOLD OA

A Novel Sparse Compositional Technique Reveals Microbial Perturbations

University of California San Diego · National Oceanic and Atmospheric Administration · +4 more institutions

PubMed
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Abstract

By accounting for the sparse compositional nature of microbiome data sets, robust Aitchison PCA can yield high discriminatory power and salient feature ranking between microbial niches. The software to perform this analysis is available under an open-source license and can be obtained at https://github.com/biocore/DEICODE; additionally, a QIIME 2 plugin is provided to perform this analysis at https://library.qiime2.org/plugins/deicode/.

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