The Comparative Toxicogenomics Database: update 2017

The Comparative Toxicogenomics Database (CTD; <inter-ref locator="http://ctdbase.org/" locator-type="url">http://ctdbase.org/</inter-ref>) provides information about interactions between chemicals and gene products, and their relationships to diseases. Core CTD content (chemical-gene, chemical-disease and gene-disease interactions manually curated from the literature) are integrated with each other as well as with select external datasets to generate expanded networks and predict novel associations. Today, core CTD includes more than 30.5 million toxicogenomic connections relating chemicals/drugs, genes/proteins, diseases, taxa, Gene Ontology (GO) annotations, pathways, and gene interaction…