Autism Spectrum Disorders and the Gut Microbiota
AFAntonella FattorussoLDLorenza Di GenovaGBGiovanni Battista Dell’IsolaEMElisabetta MencaroniSESusanna Esposito
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Abstract
In recent years, there has been an emerging interest in the possible role of the gut microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many studies have highlighted the bidirectional communication between the gut and brain (the so-called “gut-brain axis”). Accumulating evidence has shown a link between alterations in the composition of the gut microbiota and both gastrointestinal and neurobehavioural symptoms in children with ASD. The aim of this narrative review was to analyse the current knowledge about dysbiosis and gastrointestinal (GI) disorders in ASD and assess the current evidence for the role of probiotics and other non-pharmacological approaches in the treatment of…
Citation impact
476
total citations
- FWCI
- 33.03
- Percentile
- 100%
- References
- 205
Citations per year
Authors
5Topics & keywords
Topics
Keywords
- Dysbiosis
- Gut flora
- Autism
- Gut–brain axis
- Autism spectrum disorder
- Medicine
- Immunology
- Bioinformatics
UN Sustainable Development Goals
- Good health and well-being
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