articleNucleic Acids ResearchApr 20, 2016GOLD OA

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

Ontario Institute for Cancer Research · University of Toronto · +1 more institution

PubMed
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Abstract

Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse high-throughput experiments. g:Profiler studies flat and ranked gene lists and finds statistically significant Gene Ontology terms, pathways and other gene function related terms. Translation of hundreds of gene identifiers is another core feature of g:Profiler. Since its first publication in 2007, our web server has become a popular tool of choice among basic and translational researchers. Timeliness is a major advantage of g:Profiler as genome and pathway information is synchronized with the Ensembl database in quarterly updates. g:Profiler supports 213 species including mammals and other vertebrates, plants,…

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Authors

7

Topics & keywords

Keywords
  • Ensembl
  • Biology
  • Gene
  • Database
  • KEGG
  • Computational biology
  • Python (programming language)
  • Interface (matter)
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