CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture
Chinese Academy of Sciences · Institute of Genetics and Developmental Biology · +1 more institution
Abstract
Enhanced agricultural production through innovative breeding technology is urgently needed to increase access to nutritious foods worldwide. Recent advances in CRISPR/Cas genome editing enable efficient targeted modification in most crops, thus promising to accelerate crop improvement. Here, we review advances in CRISPR/Cas9 and its variants and examine their applications in plant genome editing and related manipulations. We highlight base-editing tools that enable targeted nucleotide substitutions and describe the various delivery systems, particularly DNA-free methods, that have linked genome editing with crop breeding. We summarize the applications of genome editing for trait improvement, development of…
Citation impact
- FWCI
- 63.06
- Percentile
- 100%
- References
- 192
Authors
5- KCKunling Chen
Chinese Academy of Sciences, Institute of Genetics and Developmental Biology
- YWYanpeng Wang
Chinese Academy of Sciences, Institute of Genetics and Developmental Biology
- RZRui Zhang
Chinese Academy of Sciences, Institute of Genetics and Developmental Biology
- HZHuawei Zhang
Chinese Academy of Sciences, Institute of Genetics and Developmental Biology
- CGCaixia GaoCorresponding
Chinese Academy of Sciences, Institute of Genetics and Developmental Biology, University of Chinese Academy of Sciences
Topics & keywords
- Genome editing
- CRISPR
- Genome
- Biology
- Computational biology
- Biotechnology
- Cas9
- Gene
- Zero hunger