New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx
Danish Cancer Society · Universidade de São Paulo · +6 more institutions
Abstract
The advent of Next-Generation Sequencing (NGS) technologies has opened new perspectives in deciphering the genetic mechanisms underlying complex diseases. Nowadays, the amount of genomic data is massive and substantial efforts and new tools are required to unveil the information hidden in the data. The Genomic Data Commons (GDC) Data Portal is a platform that contains different genomic studies including the ones from The Cancer Genome Atlas (TCGA) and the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiatives, accounting for more than 40 tumor types originating from nearly 30000 patients. Such platforms, although very attractive, must make sure the stored data are easily…
Citation impact
- FWCI
- 23.58
- Percentile
- 100%
- References
- 68
Authors
9Topics & keywords
- Computer science
- Context (archaeology)
- Genomics
- Data science
- Computational biology
- Data integration
- Data mining
- Bioinformatics