articleEcology and EvolutionMar 1, 2019GOLD OA

EasyCodeML: A visual tool for analysis of selection using CodeML

The University of Sydney · Fujian Agriculture and Forestry University · +1 more institution

PubMed
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Abstract

The genomic signatures of positive selection and evolutionary constraints can be detected by analyses of nucleotide sequences. One of the most widely used programs for this purpose is CodeML, part of the PAML package. Although a number of bioinformatics tools have been developed to facilitate the use of CodeML, these have various limitations. Here, we present a wrapper tool named EasyCodeML that provides a user-friendly graphical interface for using CodeML. EasyCodeML has a custom running mode in which parameters can be adjusted to meet different requirements. It also offers a preset running mode in which an evolutionary analysis pipeline and publication-quality tables can be exported by a single click.…

Citation impact

583
total citations
FWCI
22.90
Percentile
100%
References
27
Citations per year

Authors

6

Topics & keywords

Keywords
  • Computer science
  • Pipeline (software)
  • Selection (genetic algorithm)
  • Graphical user interface
  • Interface (matter)
  • Tree (set theory)
  • Data mining
  • Operating system
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