Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019
University of Manchester · Universitat de Barcelona · +22 more institutions
Abstract
Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic and biological information in order to optimise the therapeutic benefit relative to the possibility of side-effects for each individual. Recent clinical trials have shown that higher blood eosinophil counts are associated with a greater efficacy of inhaled corticosteroids (ICSs) in chronic obstructive pulmonary disease (COPD) patients. Blood eosinophil counts are a biomarker with potential to be used in clinical practice, to help target ICS treatment with more precision in COPD patients with a history of exacerbations despite appropriate bronchodilator treatment.The Global Initiative for Chronic Obstructive Lung…
Citation impact
- FWCI
- 210.84
- Percentile
- 100%
- References
- 52
Authors
21Topics & keywords
- Medicine
- Obstructive lung disease
- Intensive care medicine
- Pulmonary disease
- Lung disease
- Gold standard (test)
- Lung
- Internal medicine
- Good health and well-being
Funding
- ATAmerican Thoracic Society
- PPfizer
- AAstraZeneca
- GGlaxoSmithKline
- SSanofi
- GSGilead Sciences
- BBiogen
- TPTeva Pharmaceutical Industries
- CFChiesi Farmaceutici
- CBCSL Behring
- SSunovion
- RPRegeneron Pharmaceuticals
- VVeracyte
- YUYork University
- NINational Institute for Health and Care Research
- BFBundesministerium für Bildung und Forschung
- GGrifols
- NINational Institutes of Health
- GGenentech
- MBManchester Biomedical Research Centre