reviewInternational Journal of Molecular SciencesMar 15, 2019GOLD OA

The Therapeutic Potential of Apigenin

BSBahare SalehiAVAlessandro VendittiMSMehdi Sharifi‐RadDKDorota KręgielJSJavad Sharifi‐Rad

Bam University of Medical Sciences · Sapienza University of Rome · +9 more institutions

PubMed
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Abstract

Several plant bioactive compounds have exhibited functional activities that suggest they could play a remarkable role in preventing a wide range of chronic diseases. The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. The present work is an updated overview of apigenin, focusing on its health-promoting effects/therapeutic functions and, in particular, results of in vivo research. In addition to an introduction to its chemistry, nutraceutical features have also been described. The main key findings from in vivo research, including animal models and human studies, are summarized. The beneficial indications are reported and discussed in detail, including effects in…

Citation impact

1,186
total citations
FWCI
80.46
Percentile
100%
References
165
Citations per year

Authors

14

Topics & keywords

Topics
Keywords
  • Apigenin
  • Nutraceutical
  • Human health
  • In vivo
  • Pharmacology
  • Medicine
  • Biology
  • Biotechnology
UN Sustainable Development Goals
  • Good health and well-being
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