articleNew England Journal of MedicineMar 17, 2019BRONZE OA

Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

Duke University · Cardiovascular Institute of the South · +18 more institutions

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Abstract

Background

Appropriate antithrombotic regimens for patients with atrial fibrillation who have an acute coronary syndrome or have undergone percutaneous coronary intervention (PCI) are unclear.

Methods

inhibitor to receive apixaban or a vitamin K antagonist and to receive aspirin or matching placebo for 6 months. The primary outcome was major or clinically relevant nonmajor bleeding. Secondary outcomes included death or hospitalization and a composite of ischemic events.

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Funding