reviewNature CommunicationsMar 20, 2019GOLD OA

Coming together to define membrane contact sites

LSLuca ScorranoMAMaria Antonietta De MatteisSDScott D. EmrFGFrancesca GiordanoGHGyörgy Hajnóczky

University of Padua · Veneto Institute of Molecular Medicine · +19 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a unified vocabulary for the field. Such definitions would facilitate laying the foundations of this field, streamlining communication and resolving semantic controversies. This opinion, written by a panel of experts in the field, aims to provide this burgeoning area with guidelines for the experimental definition and analysis of contact sites. It also includes suggestions on how to operationally and tractably measure…

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740
total citations
FWCI
38.51
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100%
References
132
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Authors

15

Topics & keywords

Topics
Keywords
  • Field (mathematics)
  • Vocabulary
  • Diversity (politics)
  • Computer science
  • Data science
  • Controlled vocabulary
  • World Wide Web
  • Political science
UN Sustainable Development Goals
  • Quality Education
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