reviewMarine DrugsMar 20, 2019GOLD OA

Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies

YWYu WangMXMaochen XingQCQi CaoAJAiguo JiHLHao Liang

Shandong University

PubMed
Indexed incrossrefdoajpubmed

Abstract

The marine acid polysaccharide fucoidan has attracted attention from both the food and pharmaceutical industries due to its promising therapeutic effects. Fucoidan is a polysaccharide that mainly consists of L-fucose and sulphate groups. Its excellent biological function is attributed to its unique biological structure. Classical activities include antitumor, antioxidant, anticoagulant, antithrombotic, immunoregulatory, antiviral and anti-inflammatory effects. More recently, fucoidan has been shown to alleviate metabolic syndrome, protect the gastrointestinal tract, benefit angiogenesis and bone health. This review focuses on the progress in our understanding of the biological activities of fucoidan,…

Citation impact

475
total citations
FWCI
53.25
Percentile
100%
References
162
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Fucoidan
  • Fucose
  • Antithrombotic
  • Functional food
  • Pharmacology
  • Antioxidant
  • Polysaccharide
  • Biology
UN Sustainable Development Goals
  • Life below water
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