reviewCellsApr 3, 2019GOLD OA

Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes

Konkuk University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids, RNA, and DNA. They are derived from endocytic membranes and can transfer signals to recipient cells, thus mediating a novel mechanism of cell-to-cell communication. They are also thought to be involved in cellular waste disposal. Exosomes play significant roles in various biological functions, including the transfer of biomolecules such as RNA, proteins, enzymes, and lipids and the regulation of numerous physiological and pathological processes in various diseases. Because of these properties, they are considered to be promising biomarkers for the diagnosis and prognosis of various diseases and may contribute to the…

Citation impact

1,109
total citations
FWCI
47.68
Percentile
100%
References
308
Citations per year

Authors

5

Topics & keywords

Keywords
  • Microvesicles
  • Biogenesis
  • Endocytic cycle
  • Function (biology)
  • Computational biology
  • Cell biology
  • Biology
  • Mechanism (biology)
No related works found for this paper.

Funding