articlenpj Digital MedicineApr 4, 2019GOLD OA

Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization

Cornell University · Lander Institute · +7 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Visual morphology assessment is routinely used for evaluating of embryo quality and selecting human blastocysts for transfer after in vitro fertilization (IVF). However, the assessment produces different results between embryologists and as a result, the success rate of IVF remains low. To overcome uncertainties in embryo quality, multiple embryos are often implanted resulting in undesired multiple pregnancies and complications. Unlike in other imaging fields, human embryology and IVF have not yet leveraged artificial intelligence (AI) for unbiased, automated embryo assessment. We postulated that an AI approach trained on thousands of embryos can reliably predict embryo quality without human intervention. We…

Citation impact

450
total citations
FWCI
49.29
Percentile
100%
References
51
Citations per year

Authors

15

Topics & keywords

Keywords
  • In vitro fertilisation
  • Embryo quality
  • Embryo
  • Blastocyst
  • Embryo transfer
  • Artificial intelligence
  • Biology
  • Quality assessment
UN Sustainable Development Goals
  • Good health and well-being
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