Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
Genomics Institute of the Novartis Research Foundation · Sanford Burnham Prebys Medical Discovery Institute · +2 more institutions
Abstract
A critical component in the interpretation of systems-level studies is the inference of enriched biological pathways and protein complexes contained within OMICs datasets. Successful analysis requires the integration of a broad set of current biological databases and the application of a robust analytical pipeline to produce readily interpretable results. Metascape is a web-based portal designed to provide a comprehensive gene list annotation and analysis resource for experimental biologists. In terms of design features, Metascape combines functional enrichment, interactome analysis, gene annotation, and membership search to leverage over 40 independent knowledgebases within one integrated portal.…
Citation impact
- FWCI
- 562.58
- Percentile
- 100%
- References
- 65
Authors
8- YZYingyao ZhouCorresponding
Genomics Institute of the Novartis Research Foundation
- BZBin Zhou
Genomics Institute of the Novartis Research Foundation
- LPLars Pache
Sanford Burnham Prebys Medical Discovery Institute, Discovery Institute
- MWMax W. Chang
University of California San Diego
- AHAlireza Hadj Khodabakhshi
Genomics Institute of the Novartis Research Foundation
Topics & keywords
- Computer science
- Interactome
- Annotation
- Inference
- Pipeline (software)
- Leverage (statistics)
- Resource (disambiguation)
- Data science