reviewBioMed Research InternationalApr 7, 2019HYBRID OA

Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases

CFCinzia ForniFFFrancesco FacchianoMBManuela BartoliSPStefano PierettiAFAntonio Facchiano

University of Rome Tor Vergata · Istituto Superiore di Sanità · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage to DNA, proteins, and lipids, leading to important cellular dysfunctions. The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases. The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective…

Citation impact

511
total citations
FWCI
23.58
Percentile
100%
References
173
Citations per year

Authors

12

Topics & keywords

Topics
Keywords
  • Oxidative stress
  • Reactive oxygen species
  • Antioxidant
  • Disease
  • Diabetes mellitus
  • Inflammation
  • Biology
  • DNA damage
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding