article˜The œLancet. Gastroenterology & hepatologyApr 10, 2019HYBRID OA

A global scientific strategy to cure hepatitis B

The Royal Melbourne Hospital · Victorian Infectious Diseases Reference Laboratory · +30 more institutions

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Abstract

Chronic hepatitis B virus (HBV) infection is a global public health challenge on the same scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE-HBV) is a coalition of experts dedicated to accelerating the discovery of a cure for chronic hepatitis B. Following extensive consultation with more than 50 scientists from across the globe, as well as key stakeholders including people affected by HBV, we have identified gaps in our current knowledge and new strategies and tools that are required to achieve HBV cure. We believe that research must focus on the discovery of interventional strategies that will permanently reduce the number of productively infected cells or permanently…

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