articleNucleic Acids ResearchApr 11, 2019GOLD OA

AutoMLST: an automated web server for generating multi-locus species trees highlighting natural product potential

MAMohammad AlanjaryKSKat SteinkeNZNadine Ziemert

German Center for Infection Research · University of Tübingen

PubMed
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Abstract

Understanding the evolutionary background of a bacterial isolate has applications for a wide range of research. However generating an accurate species phylogeny remains challenging. Reliance on 16S rDNA for species identification currently remains popular. Unfortunately, this widespread method suffers from low resolution at the species level due to high sequence conservation. Currently, there is now a wealth of genomic data that can be used to yield more accurate species designations via modern phylogenetic methods and multiple genetic loci. However, these often require extensive expertise and time. The Automated Multi-Locus Species Tree (autoMLST) was thus developed to provide a rapid 'one-click' pipeline to…

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Topics & keywords

Topics
Keywords
  • Biology
  • Locus (genetics)
  • Web server
  • Web application
  • Computational biology
  • World Wide Web
  • The Internet
  • Genetics
UN Sustainable Development Goals
  • Life in Land
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