Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery
National Institutes of Health · National Institute of Biomedical Imaging and Bioengineering · +1 more institution
Abstract
Abstract Fluorescence bioimaging affords a vital tool for both researchers and surgeons to molecularly target a variety of biological tissues and processes. This review focuses on summarizing organic dyes emitting at a biological transparency window termed the near‐infrared‐II (NIR‐II) window, where minimal light interaction with the surrounding tissues allows photons to travel nearly unperturbed throughout the body. NIR‐II fluorescence imaging overcomes the penetration/contrast bottleneck of imaging in the visible region, making it a remarkable modality for early diagnosis of cancer and highly sensitive tumor surgery. Due to their convenient bioconjugation with peptides/antibodies, NIR‐II molecular dyes are…
Citation impact
- FWCI
- 48.52
- Percentile
- 100%
- References
- 154
Authors
5- SZShoujun Zhu
National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering
- RTRui Tian
National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering
- ALAlexander L. Antaris
Stanford University
- XCXiaoyuan ChenCorresponding
National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering
- HDHongjie DaiCorresponding
Stanford University
Topics & keywords
- Bioconjugation
- Autofluorescence
- Molecular imaging
- Cancer surgery
- Near-infrared spectroscopy
- Materials science
- Fluorescence
- Fluorescence-lifetime imaging microscopy