Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues

Biological membranes are key elements for the maintenance of cell architecture and physiology. Beyond a pure barrier separating the inner space of the cell from the outer, the plasma membrane is a scaffold and player in cell-to-cell communication and the initiation of intracellular signals among other functions. Critical to this function is the plasma membrane compartmentalization in lipid microdomains that control the localization and productive interactions of proteins involved in cell signal propagation. In addition, cells are divided into compartments limited by other membranes whose integrity and homeostasis are finely controlled, and which determine the identity and function of the different organelles.…

• FL
  Fundació la Marató de TV3
• EC
  European Commission

  Awards: 755179, 627441, H2020, PIEF-GA-2013-627441
• MD
  Ministerio de Economía y Competitividad

  Awards: DI-17-09187, RTC-2015-3542, RTC-2015-4094
• H2
  Horizon 2020 Framework Programme

  Award: 755179
• SF
  Seventh Framework Programme

  Award: PIEF-GA-2013-627441
• ER
  European Regional Development Fund

  Awards: RTC-2015-4094, H2020, RTC-2015-3542
• ES
  European Social Fund

  Award: PD/036/2016