antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
Novo Nordisk Foundation · Technical University of Denmark · +4 more institutions
Abstract
Secondary metabolites produced by bacteria and fungi are an important source of antimicrobials and other bioactive compounds. In recent years, genome mining has seen broad applications in identifying and characterizing new compounds as well as in metabolic engineering. Since 2011, the 'antibiotics and secondary metabolite analysis shell-antiSMASH' (https://antismash.secondarymetabolites.org) has assisted researchers in this, both as a web server and a standalone tool. It has established itself as the most widely used tool for identifying and analysing biosynthetic gene clusters (BGCs) in bacterial and fungal genome sequences. Here, we present an entirely redesigned and extended version 5 of antiSMASH.…
Citation impact
- FWCI
- 383.47
- Percentile
- 100%
- References
- 43
Authors
8- KBKai Blin
Novo Nordisk Foundation, Technical University of Denmark
- SJSimon J. Shaw
Novo Nordisk Foundation, Technical University of Denmark
- KSKat Steinke
German Center for Infection Research, University of Tübingen
- RVRasmus Villebro
Novo Nordisk Foundation, Technical University of Denmark
- NZNadine Ziemert
German Center for Infection Research, University of Tübingen
Topics & keywords
- Biology
- Pipeline (software)
- Metabolite
- Genome
- Computational biology
- Genetics
- Gene
- Computer science