articleRadiologyMay 7, 2019Closed access

A Deep Learning Mammography-based Model for Improved Breast Cancer Risk Prediction

Massachusetts General Hospital

PubMed
Indexed incrossrefpubmed

Abstract

Background Mammographic density improves the accuracy of breast cancer risk models. However, the use of breast density is limited by subjective assessment, variation across radiologists, and restricted data. A mammography-based deep learning (DL) model may provide more accurate risk prediction. Purpose To develop a mammography-based DL breast cancer risk model that is more accurate than established clinical breast cancer risk models. Materials and Methods This retrospective study included 88 994 consecutive screening mammograms in 39 571 women between January 1, 2009, and December 31, 2012. For each patient, all examinations were assigned to either training, validation, or test sets, resulting in 71 689, 8554,…

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724
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56.26
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100%
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Authors

5

Topics & keywords

Keywords
  • Medicine
  • Breast cancer
  • Mammography
  • Logistic regression
  • Confidence interval
  • Receiver operating characteristic
  • Breast imaging
  • Risk factor
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