Fluorescent probes for organelle-targeted bioactive species imaging

), ATP, HCHO, CO and so on, are a highly important category of molecules in living cells. The dynamic fluctuations of these molecules in subcellular microenvironments determine cellular homeostasis, signal conduction, immunity and metabolism. However, their abnormal expressions can cause disorders which are associated with diverse major diseases. Monitoring bioactive molecules in subcellular structures is therefore critical for bioanalysis and related drug discovery. With the emergence of organelle-targeted fluorescent probes, significant progress has been made in subcellular imaging. Among the developed subcellular localization fluorescent tools, ROS, RNS and RSS (RONSS) probes are highly attractive, owing to…

• NN
  National Natural Science Foundation of China

  Awards: 21874086, 21775094, 91753111, 21535004
• KT
  Key Technology Research and Development Program of Shandong

  Award: 2018YFJH0502