Combining Nanomedicine and Immunotherapy
Universitätsklinikum Aachen · RWTH Aachen University · +2 more institutions
Abstract
ConspectusNanomedicine holds significant potential to improve the efficacy of cancer immunotherapy. Thus far, nanomedicines, i.e., 1–100(0) nm sized drug delivery systems, have been primarily used to improve the balance between the efficacy and toxicity of conjugated or entrapped chemotherapeutic drugs. The clinical performance of cancer nanomedicines has been somewhat disappointing, which is arguably mostly due to the lack of tools and technologies for patient stratification. Conversely, the clinical progress made with immunotherapy has been spectacular, achieving complete cures and inducing long-term survival in advanced-stage patients. Unfortunately, however, immunotherapy only works well in relatively…
Citation impact
- FWCI
- 24.64
- Percentile
- 100%
- References
- 86
Authors
2Topics & keywords
- Immunotherapy
- Tumor microenvironment
- Cancer immunotherapy
- Immune system
- Nanomedicine
- Medicine
- Cancer research
- Cancer
- Good health and well-being