Natural Berberine-Based Chinese Herb Medicine Assembled Nanostructures with Modified Antibacterial Application
Beijing University of Chinese Medicine · Chinese Academy of Sciences · +1 more institution
Abstract
The abuse of traditional antibiotics has caused a series of health problems including antimicrobial resistance, which threatens human health. Therefore, searching for broad sources of antimicrobial agents and developing multidimensional strategies to combat bacterial infections are urgent. Here, we reported two natural self-assembling modes between berberine (BBR) and flavonoid glycosides: nanoparticles (NPs) and nanofibers (NFs), which were both mainly governed by electrostatic and hydrophobic interactions. These two nanostructures exhibited different antibacterial properties from BBR. NPs showed significantly enhanced bacteriostatic activity, whereas NFs displayed a much weaker effect than BBR. The…
Citation impact
- FWCI
- 23.72
- Percentile
- 100%
- References
- 47
Authors
11Topics & keywords
- Antibacterial activity
- Berberine
- Antimicrobial
- Chemistry
- Biocompatibility
- Nanotechnology
- Bacteria
- Materials science
- Good health and well-being