Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with chronic pulmonary infections wreak havoc upon the airway, leading to a disease course of substantial morbidity and shortened life span.

• NI
  National Institutes of Health

  Awards: R01AI097511, R01AI34895
• CF
  Center for Clinical and Translational Science, Ohio State University

  Award: TL1TR001069