articleNature Chemical BiologyJun 9, 2019GREEN OA

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

WFWilliam FarnabyMKManfred KoeglMJMichael J. RoyCWClaire WhitworthEDEmelyne Diers

University of Dundee · Boehringer Ingelheim (Austria)

PubMed
Indexed incrossrefpubmed

Abstract

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571
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100%
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37

Topics & keywords

Topics
Keywords
  • SMARCA4
  • Bromodomain
  • Ubiquitin ligase
  • Cell biology
  • Ubiquitin
  • Chromatin remodeling
  • Cancer research
  • AAA proteins
UN Sustainable Development Goals
  • Good health and well-being
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