Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications
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Abstract
During the past two decades, tissue engineering and the regenerative medicine field have invested in the regeneration and reconstruction of pathologically altered tissues, such as cartilage, bone, skin, heart valves, nerves and tendons, and many others. The 3D structured scaffolds and hydrogels alone or combined with bioactive molecules or genes and cells are able to guide the development of functional engineered tissues, and provide mechanical support during in vivo implantation. Naturally derived and synthetic polymers, bioresorbable inorganic materials, and respective hybrids, and decellularized tissue have been considered as scaffolding biomaterials, owing to their boosted structural, mechanical, and…
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7Topics & keywords
Topics
Keywords
- Regenerative medicine
- Scaffold
- Tissue engineering
- Decellularization
- Self-healing hydrogels
- Regeneration (biology)
- Biomedical engineering
- Biocompatible material
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