reviewMaterialsJun 5, 2019GOLD OA

Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications

University of Minho

PubMed
Indexed incrossrefdoajpubmed

Abstract

During the past two decades, tissue engineering and the regenerative medicine field have invested in the regeneration and reconstruction of pathologically altered tissues, such as cartilage, bone, skin, heart valves, nerves and tendons, and many others. The 3D structured scaffolds and hydrogels alone or combined with bioactive molecules or genes and cells are able to guide the development of functional engineered tissues, and provide mechanical support during in vivo implantation. Naturally derived and synthetic polymers, bioresorbable inorganic materials, and respective hybrids, and decellularized tissue have been considered as scaffolding biomaterials, owing to their boosted structural, mechanical, and…

Citation impact

490
total citations
FWCI
26.71
Percentile
100%
References
229
Citations per year

Authors

7

Topics & keywords

Keywords
  • Regenerative medicine
  • Scaffold
  • Tissue engineering
  • Decellularization
  • Self-healing hydrogels
  • Regeneration (biology)
  • Biomedical engineering
  • Biocompatible material
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