A Review of the Microbial Production of Bioactive Natural Products and Biologics

A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous medical agents with widely divergent chemical structures and biological activities, including antimicrobial, immunosuppressive, anticancer, and anti-inflammatory activities, many of which have been developed as treatments and have potential therapeutic applications for human diseases. Aside from natural products, the recent development of recombinant DNA technology has sparked the development of a wide array of biopharmaceutical products, such as recombinant proteins, offering significant advances in treating a…

• NR
  National Research Foundation
• EW
  Ewha Womans University

  Award: RP-Grant 2019
• MO
  Ministry of Oceans and Fisheries

  Awards: 20180430, No. 20180430
• RD
  Rural Development Administration
• NR
  National Research Foundation of Korea

  Awards: 2019R1A2B5B03069338, 2018M3A9F3079662
• CO
  Centre of Excellence for Biosecurity Risk Analysis
• KI
  Korea Institute of Marine Science and Technology promotion

  Awards: 20180430, No. 20180430
• MO
  Ministry of Science and ICT, South Korea

  Awards: 2018M3A9F3079662, 2019R1A2B5B03069338