reviewAdvanced ScienceJun 14, 2019GOLD OA

Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

University of Wollongong · Illawarra Health and Medical Research Institute · +12 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Given their durability and long-term stability, self-healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility between hydrogel toughness and rapid self-healing remains unaddressed, and therefore most of the self-healable hydrogels still face serious challenges within the dynamic and mechanically demanding environment of human organs/tissues. Furthermore, depending on the target tissue, the self-healing hydrogels must comply with a wide range of properties including electrical, biological, and mechanical. Notably, the incorporation of nanomaterials into double-network…

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