Consolidation alters motor sequence-specific distributed representations
Centre National de la Recherche Scientifique · Inserm · +6 more institutions
Abstract
Functional magnetic resonance imaging (fMRI) studies investigating the acquisition of sequential motor skills in humans have revealed learning-related functional reorganizations of the cortico-striatal and cortico-cerebellar motor systems accompanied with an initial hippocampal contribution. Yet, the functional significance of these activity-level changes remains ambiguous as they convey the evolution of both sequence-specific knowledge and unspecific task ability. Moreover, these changes do not specifically assess the occurrence of learning-related plasticity. To address these issues, we investigated local circuits tuning to sequence-specific information using multivariate distances between patterns evoked by…
Citation impact
- FWCI
- 85.45
- Percentile
- 100%
- References
- 112
Authors
6- BPBasile PinsardCorresponding
Centre National de la Recherche Scientifique, Inserm, Sorbonne Université, Laboratoire d’Imagerie Biomédicale, Institut Universitaire de Gériatrie de Montréal
- ABArnaud Boutin
Montreal Neurological Institute and Hospital, Institut Universitaire de Gériatrie de Montréal, McGill University
- EGElla Gabitov
Montreal Neurological Institute and Hospital, Institut Universitaire de Gériatrie de Montréal, McGill University
- OLOvidiu Lungu
Institut Universitaire de Gériatrie de Montréal
- HBHabib Benali
Centre National de la Recherche Scientifique, Inserm, Sorbonne Université, Laboratoire d’Imagerie Biomédicale, Concordia University
Topics & keywords
- Neuroscience
- Memory consolidation
- Functional magnetic resonance imaging
- Striatum
- Motor learning
- Procedural memory
- Sequence learning
- Motor skill
- Quality Education