reviewBrainMay 13, 2019BRONZE OA

Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines

MFMassimo FilippiPPPaolo PreziosaBBBrenda BanwellFBFrederik BarkhofOCOlga Ciccarelli

Vita-Salute San Raffaele University · Istituti di Ricovero e Cura a Carattere Scientifico · +27 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some diseases, now recognized as conditions distinct from multiple sclerosis, may satisfy the MRI criteria for multiple sclerosis (e.g. neuromyelitis optica spectrum disorders, Susac syndrome), thus making the diagnosis of multiple sclerosis more challenging, especially if biomarker testing (such as serum anti-AQP4 antibodies) is not informative. Improvements in MRI technology contribute and promise to better define the typical features of multiple sclerosis lesions (e.g. juxtacortical and periventricular location, cortical involvement).…

Citation impact

547
total citations
FWCI
35.35
Percentile
100%
References
127
Citations per year

Authors

17

Topics & keywords

Topics
Keywords
  • Multiple sclerosis
  • Neuromyelitis optica
  • Medicine
  • Magnetic resonance imaging
  • McDonald criteria
  • Medical diagnosis
  • Pathology
  • Radiology
UN Sustainable Development Goals
  • Good health and well-being
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