reviewFrontiers in Public HealthJul 2, 2019GOLD OA

Chagas Disease: From Discovery to a Worldwide Health Problem

Universidade Federal do Paraná · Hospital de Clínicas Universidade Federal do Paraná · +2 more institutions

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Abstract

Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of the disease, characterized by its etiological agent (Trypanosoma cruzi) and identified its insect vector. Initially, CD occurred only in Latin America and was considered a silent and poorly visible disease. More recently, CD became a neglected worldwide disease with a high morbimortality rate and substantial social impact, emerging as a significant public health threat. In this context, it is crucial to better understand better the epidemiological scenarios of CD and its transmission dynamics, involving people infected and at risk of infection, diversity…

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