Recent advances in the synthesis of axially chiral biaryls via transition metal-catalysed asymmetric C–H functionalization
Hangzhou Academy of Agricultural Sciences · Zhejiang University
Abstract
Axially chiral biaryl motifs are widely present in natural products and pharmaceuticals. Moreover, they have been broadly used as privileged ligands in asymmetric catalysis. Over the past few decades, the efficient synthesis of axially chiral biaryls has been a research topic of great interest. This feature article will provide an overview of recent advances in the synthesis of these chiral skeletons via transition metal-catalysed asymmetric C-H functionalization.
Citation impact
- FWCI
- 26.40
- Percentile
- 100%
- References
- 96
Authors
4- GLGang Liao
Hangzhou Academy of Agricultural Sciences, Zhejiang University
- TZTao Zhou
Hangzhou Academy of Agricultural Sciences, Zhejiang University
- QYQi‐Jun Yao
Hangzhou Academy of Agricultural Sciences, Zhejiang University
- BSBing‐Feng ShiCorresponding
Hangzhou Academy of Agricultural Sciences, Zhejiang University
Topics & keywords
- Surface modification
- Transition metal
- Axial symmetry
- Chemistry
- Catalysis
- Combinatorial chemistry
- Enantioselective synthesis
- Metal
Funding
- NNNational Natural Science Foundation of ChinaAwards: 21422206, 21772170, 21572201
- CPChina Postdoctoral Science FoundationAwards: 2017M621906, 2019M650135
- NKNational Key Research and Development Program of ChinaAward: 2015CB856600
- FRFundamental Research Funds for the Central UniversitiesAward: 2018XZZX001-02
- NSNatural Science Foundation of Zhejiang ProvinceAward: LR17B020001