reviewBerichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformaticsJul 13, 2019DIAMOND OA

Non-Coding RNAs and their Integrated Networks

PZPeijing ZhangWWWenyi WuQCQi ChenMCMing Chen

State Key Laboratory of Plant Physiology and Biochemistry · Zhejiang University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are different types of non-coding RNAs that modulate complex molecular and cellular processes. RNA sequencing technologies and bioinformatics methods greatly promoted the study of ncRNAs, which revealed ncRNAs' essential roles in diverse aspects of biological functions. As important key players in gene regulatory networks, ncRNAs work with other biomolecules, including coding and non-coding RNAs, DNAs and proteins. In this review, we discuss the distinct types of ncRNAs, including housekeeping ncRNAs and regulatory ncRNAs, their versatile functions and interactions, transcription, translation, and modification. Moreover, we…

Citation impact

675
total citations
FWCI
18.54
Percentile
100%
References
115
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Non-coding RNA
  • Computational biology
  • RNA
  • Biology
  • microRNA
  • Gene
  • Long non-coding RNA
  • Genome
No related works found for this paper.

Funding