Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

With the aging population, prevalence of neurodegenerative diseases is increasing, thus placing a growing burden on individuals and the whole society. However, individual rates of aging are shaped by a great variety of and the interactions between environmental, genetic, and epigenetic factors. Establishing biomarkers of the neuroanatomical aging processes exemplifies a new trend in neuroscience in order to provide risk-assessments and predictions for age-associated neurodegenerative and neuropsychiatric diseases at a single-subject level. The “Brain Age Gap Estimation (BrainAGE)” method constitutes the first and actually most widely applied concept for predicting and evaluating individual brain age based on…

• DF
  Deutsche Forschungsgemeinschaft

  Awards: FR 3709/1-1 to KF, FR 3709/1-1, 3709/1-1
• UJ
  Universitätsklinikum Jena
• FH
  FP7 Health

  Award: 279281