Bioinspired mechanically active adhesive dressings to accelerate wound closure
Harvard University · University of California, San Francisco · +2 more institutions
Abstract
Inspired by embryonic wound closure, we present mechanically active dressings to accelerate wound healing. Conventional dressings passively aid healing by maintaining moisture at wound sites. Recent developments have focused on drug and cell delivery to drive a healing process, but these methods are often complicated by drug side effects, sophisticated fabrication, and high cost. Here, we present novel active adhesive dressings consisting of thermoresponsive tough adhesive hydrogels that combine high stretchability, toughness, tissue adhesion, and antimicrobial function. They adhere strongly to the skin and actively contract wounds, in response to exposure to the skin temperature. In vitro and in vivo studies…
Citation impact
- FWCI
- 40.02
- Percentile
- 100%
- References
- 57
Authors
6Topics & keywords
- Adhesive
- Wound closure
- Closure (psychology)
- Wound healing
- Biomedical engineering
- Medicine
- Materials science
- Surgery
- Zero hunger