Mesenchymal Stem Cells for Regenerative Medicine
Union Hospital · Jilin University · +3 more institutions
Abstract
In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and synovium, and differentiate into various cell lineages according to the requirements of specific biomedical applications. As MSCs do not express significant histocompatibility complexes and immune stimulating molecules, they are not detected by immune surveillance and do not lead to graft rejection after transplantation. These properties make them competent biomedical candidates, especially in tissue engineering. We present a brief overview of MSC extraction methods and subsequent potential for differentiation, and a comprehensive overview…
Citation impact
- FWCI
- 76.00
- Percentile
- 100%
- References
- 261
Authors
8- YHYu HanCorresponding
Union Hospital, Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Second Affiliated Hospital of Jilin University
- YHYu Han
Union Hospital, Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Second Affiliated Hospital of Jilin University
- XLXuezhou Li
Union Hospital, Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Second Affiliated Hospital of Jilin University
- YZYanbo ZhangCorresponding
Union Hospital, Jilin University
- YHYuping Han
Union Hospital, Jilin University, Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Second Affiliated Hospital of Jilin University
Topics & keywords
- Mesenchymal stem cell
- Regenerative medicine
- Immune system
- Stem cell
- Transplantation
- Tissue engineering
- Medicine
- Biology
- Good health and well-being
Funding
- JPJilin Province Development and Reform CommissionAward: 2018C052-4
- NNNational Natural Science Foundation of ChinaAwards: 2019005, 51803006, 81671804, 51873207, 51803006, 81701811, 51673190, and 81671804, 51673190, 81701811, 20190201068JC, 51873207
- CAChinese Academy of Sciences
- PGPeople's Government of Jilin Province
- YIYouth Innovation Promotion Association of the Chinese Academy of SciencesAward: 2019005
- NSNatural Science Foundation of Shandong ProvinceAward: ZR2018BH008
- YIYouth Innovation Promotion Association