reviewCellsAug 13, 2019GOLD OA

Mesenchymal Stem Cells for Regenerative Medicine

Union Hospital · Jilin University · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and synovium, and differentiate into various cell lineages according to the requirements of specific biomedical applications. As MSCs do not express significant histocompatibility complexes and immune stimulating molecules, they are not detected by immune surveillance and do not lead to graft rejection after transplantation. These properties make them competent biomedical candidates, especially in tissue engineering. We present a brief overview of MSC extraction methods and subsequent potential for differentiation, and a comprehensive overview…

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