Marine Natural Products: A Source of Novel Anticancer Drugs
Karolinska University Hospital · Stockholm University · +15 more institutions
Abstract
Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of action and thus considerable research has been conducted for new anticancer drugs from natural sources, especially plants, microbes and marine organisms. Marine populations represent reservoirs of novel bioactive metabolites with diverse groups of chemical structures. This review highlights the impact of marine organisms, with particular emphasis on marine plants, algae, bacteria, actinomycetes, fungi, sponges and soft corals. Anti-cancer effects of marine natural products in in vitro and in vivo studies were first introduced; their activity in the prevention of tumor formation and the related…
Citation impact
- FWCI
- 46.82
- Percentile
- 100%
- References
- 234
Authors
16Topics & keywords
- Biology
- Chemical space
- Marine fungi
- Computational biology
- Drug discovery
- Ecology
- Bioinformatics
- Life below water