Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels
Weill Cornell Medical College in Qatar · Comenius University Bratislava · +2 more institutions
Abstract
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming incidence rate and a huge burden on health care providers. DM is characterized by the elevation of blood glucose due either to a defect in insulin synthesis, secretion, binding to receptor, or an increase of insulin resistance. The internal and external factors such as obesity, urbanizations, and genetic mutations could increase the risk of developing DM. Flavonoids are phenolic compounds existing as secondary metabolites in fruits and vegetables as well as fungi. Their structure consists of 15 carbon skeletons and two aromatic rings (A and B) connected by three carbon chains. Flavonoids are furtherly classified into 6…
Citation impact
- FWCI
- 37.75
- Percentile
- 100%
- References
- 256
Authors
5- RKRaghad Khalid AL-Ishaq
Weill Cornell Medical College in Qatar
- MAMariam Abotaleb
Weill Cornell Medical College in Qatar
- PKPeter Kubatka
Comenius University Bratislava
- KKKarol Kajo
St. Elizabeth Hospital in Enumclaw, Biomedical Research Center of the Slovak Academy of Sciences
- DBDietrich BüsselbergCorresponding
Weill Cornell Medical College in Qatar
Topics & keywords
- Diabetes mellitus
- Flavones
- Insulin resistance
- Flavanone
- Flavonols
- Pharmacology
- Insulin receptor
- Isoflavones
- Sustainable cities and communities