Efficient Angiogenesis-Based Diabetic Wound Healing/Skin Reconstruction through Bioactive Antibacterial Adhesive Ultraviolet Shielding Nanodressing with Exosome Release
Xi'an Jiaotong University · Wenzhou Medical University · +4 more institutions
Abstract
Diabetic wound healing and angiogenesis remain a worldwide challenge for both clinic and research. The use of adipose stromal cell derived exosomes delivered by bioactive dressing provides a potential strategy for repairing diabetic wounds with less scar formation and fast healing. In this study, we fabricated an injectable adhesive thermosensitive multifunctional polysaccharide-based dressing (FEP) with sustained pH-responsive exosome release for promoting angiogenesis and diabetic wound healing. The FEP dressing possessed multifunctional properties including efficient antibacterial activity/multidrug-resistant bacteria, fast hemostatic ability, self-healing behavior, and tissue-adhesive and good UV-shielding…
Citation impact
- FWCI
- 38.52
- Percentile
- 100%
- References
- 77
Authors
12- MWMin Wang
Xi'an Jiaotong University
- CWChenggui Wang
Wenzhou Medical University, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Second Affiliated Hospital of Zhejiang University
- MCMi Chen
Xi'an Jiaotong University
- YXYuewei Xi
Xi'an Jiaotong University
- WCWei Cheng
Xi'an Jiaotong University
Topics & keywords
- Wound healing
- Angiogenesis
- Granulation tissue
- Medicine
- In vivo
- Biomedical engineering
- Pharmacology
- Materials science