articleJournal of Cardiovascular Disease ResearchJan 1, 2010Closed access

Excitation-Contraction Coupling and Cardiac Contractile Force

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Abstract

1. Major cellular structures involved in E-C coupling. 2. Myofilaments: The end effector of E-C Coupling. 3. Sources and sinks of activator calcium. 4. Cardiac action potentials and ion channels. 5. Ca influx via sarcolemmal Ca channels. 6. Na/Ca exchange and the sarcolemmal Ca-pump. 7. Sarcoplasmic reticulum Ca uptake, content and release. 8. Excitation-contraction coupling. 9. Control of cardiac contraction by SR and sarcolemmal Ca fluxes. 10. Cardiac inotropy and Ca mismanagement. References. Index.

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Topics & keywords

Keywords
  • Myofilament
  • Contraction (grammar)
  • Sarcolemma
  • Biophysics
  • Excitation–contraction coupling
  • Endoplasmic reticulum
  • Calcium
  • Medicine
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