reviewInternational Journal of Molecular SciencesOct 11, 2019GOLD OA

Effects of Omega-3 Fatty Acids on Immune Cells

University of Gothenburg

PubMed
Indexed incrossrefdoajpubmed

Abstract

Alterations on the immune system caused by omega-3 fatty acids have been described for 30 years. This family of polyunsaturated fatty acids exerts major alterations on the activation of cells from both the innate and the adaptive immune system, although the mechanisms for such regulation are diverse. First, as a constitutive part of the cellular membrane, omega-3 fatty acids can regulate cellular membrane properties, such as membrane fluidity or complex assembly in lipid rafts. In recent years, however, a new role for omega-3 fatty acids and their derivatives as signaling molecules has emerged. In this review, we describe the latest findings describing the effects of omega-3 fatty acids on different cells from…

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574
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40.36
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100%
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170
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Authors

3

Topics & keywords

Keywords
  • Immune system
  • Polyunsaturated fatty acid
  • Lipid raft
  • Biology
  • Biochemistry
  • Acquired immune system
  • Membrane fluidity
  • Cell signaling
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