Recent Progress in Ferroptosis Inducers for Cancer Therapy
City University of Hong Kong · Nanjing Tech University · +2 more institutions
Abstract
Ferroptosis is a newly discovered form of regulated cell death that is the nexus between metabolism, redox biology, and human health. Emerging evidence shows the potential of triggering ferroptosis for cancer therapy, particularly for eradicating aggressive malignancies that are resistant to traditional therapies. Recently, there has been a great deal of effort to design and develop anticancer drugs based on ferroptosis induction. Recent advances of ferroptosis-inducing agents at the intersection of chemistry, materials science, and cancer biology are presented. The basis of ferroptosis is summarized first to highlight the feasibility and characteristics of triggering ferroptosis for cancer therapy. A…
Citation impact
- FWCI
- 135.66
- Percentile
- 100%
- References
- 160
Authors
4- CLChen Liang
City University of Hong Kong
- XZXinglin Zhang
Nanjing Tech University
- MYMengsu YangCorresponding
City University of Hong Kong, City University of Hong Kong, Shenzhen Research Institute
- XDXiaochen DongCorresponding
Nanjing Tech University, Nanjing University of Information Science and Technology
Topics & keywords
- Cancer therapy
- Nexus (standard)
- Inducer
- Cancer
- Human health
- Nanotechnology
- Biology
- Cancer research
- Good health and well-being