A Perspective on Polylactic Acid-Based Polymers Use for Nanoparticles Synthesis and Applications
University of Applied Sciences and Arts of Southern Switzerland · Politecnico di Milano · +1 more institution
Abstract
Polylactic acid (PLA) – based polymers are ubiquitous in the biomedical field thanks to their combination of attractive peculiarities: biocompatibility (degradation products do not elicit critical responses and are easily metabolized by the body), hydrolytic degradation in situ, tailorable properties and well–established processing technologies. This led to the development of several applications, such as bone fixation screws, bioresorbable suture threads and stent coating, just to name a few. Nanomedicine could not be unconcerned by PLA–based materials as well, where their use for the synthesis of nanocarriers for the targeted delivery of hydrophobic drugs emerged as a new promising application. The purpose…
Citation impact
- FWCI
- 17.11
- Percentile
- 100%
- References
- 84
Authors
4- TCTommaso CasaliniCorresponding
University of Applied Sciences and Arts of Southern Switzerland
- FRFilippo Rossi
Politecnico di Milano
- ACA. Castrovinci
University of Applied Sciences and Arts of Southern Switzerland
- GPGiuseppe Perale
University of Applied Sciences and Arts of Southern Switzerland, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology
Topics & keywords
- Polylactic acid
- Nanoparticle
- Perspective (graphical)
- Polymer
- Materials science
- Nanotechnology
- Chemistry
- Computer science