Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression
Institute of Psychology, Chinese Academy of Sciences · Institute of Physics · +3 more institutions
Abstract
Rumination is strongly and consistently correlated with depression. Although multiple studies have explored the neural correlates of rumination, findings have been inconsistent and the mechanisms underlying rumination remain elusive. Functional brain imaging studies have identified areas in the default mode network (DMN) that appear to be critically involved in ruminative processes. However, a meta-analysis to synthesize the findings of brain regions underlying rumination is currently lacking. Here, we conducted a meta-analysis consisting of experimental tasks that investigate rumination by using Signed Differential Mapping of 14 fMRI studies comprising 286 healthy participants. Furthermore, rather than treat…
Citation impact
- FWCI
- 25.54
- Percentile
- 100%
- References
- 82
Authors
8- HZHuixia Zhou
Institute of Psychology, Chinese Academy of Sciences, Institute of Physics, University of Chinese Academy of Sciences
- XCXiao Chen
Institute of Psychology, Chinese Academy of Sciences, Institute of Physics, University of Chinese Academy of Sciences
- YSYangqian Shen
Institute of Psychology, Chinese Academy of Sciences
- LLLe Li
Institute of Psychology, Chinese Academy of Sciences, Institute of Physics, University of Chinese Academy of Sciences
- NCNing-Xuan Chen
Institute of Psychology, Chinese Academy of Sciences, Institute of Physics, University of Chinese Academy of Sciences
Topics & keywords
- Rumination
- Default mode network
- Psychology
- Neuroscience
- Meta-analysis
- Functional magnetic resonance imaging
- Prefrontal cortex
- Neuroimaging