Schizophrenia—An Overview
King's College London · Hammersmith Hospital · +2 more institutions
Abstract
Importance: Schizophrenia is a common, severe mental illness that most clinicians will encounter regularly during their practice. This report provides an overview of the clinical characteristics, epidemiology, genetics, neuroscience, and psychopharmacology of schizophrenia to provide a basis to understand the disorder and its treatment. This educational review is integrated with a clinical case to highlight how recent research findings can inform clinical understanding. Observations: The first theme considered is the role of early-life environmental and genetic risk factors in altering neurodevelopmental trajectories to predispose an individual to the disorder and leading to the development of prodromal…
Citation impact
- FWCI
- 59.49
- Percentile
- 100%
- References
- 103
Authors
3- RARobert A. McCutcheonCorresponding
King's College London, Hammersmith Hospital, Imperial College London, Medical Research Council
- TRTiago Reis Marques
King's College London, Hammersmith Hospital, Imperial College London, Medical Research Council
- OHOliver Howes
King's College London, Hammersmith Hospital, Imperial College London, Medical Research Council
Topics & keywords
- Schizophrenia (object-oriented programming)
- Psychosocial
- Psychology
- Neuroscience
- Psychiatry
- Cognition
- Psychosis
- Mechanism (biology)