Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases
Visva-Bharati University · University of North Texas · +2 more institutions
Abstract
Reactive species produced in the cell during normal cellular metabolism can chemically react with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing their oxidative modifications leading to alterations in their compositions and potential damage to their cellular activities. Fortunately, cells have evolved several antioxidant defense mechanisms (as metabolites, vitamins, and enzymes) to neutralize or mitigate the harmful effect of reactive species and/or their byproducts. Any perturbation in the balance in the level of antioxidants and the reactive species results in a physiological condition called “oxidative stress.” A catalase is one of the crucial antioxidant enzymes that…
Citation impact
- FWCI
- 42.44
- Percentile
- 100%
- References
- 163
Authors
4Topics & keywords
- Catalase
- Oxidative stress
- Reactive oxygen species
- Antioxidant
- Superoxide dismutase
- Diabetes mellitus
- Disease
- Oxidative phosphorylation