reviewNature Reviews Drug DiscoveryNov 11, 2019Closed access

Synthetic lethality as an engine for cancer drug target discovery

AHAlan HuangLALevi A. GarrawayAAAlan AshworthBLBarbara L. Weber

Tango Therapeutics (United States) · Eli Lilly (United States) · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

466
total citations
FWCI
19.40
Percentile
100%
References
217
Citations per year

Authors

4

Topics & keywords

Topics
Keywords
  • Druggability
  • Synthetic lethality
  • CRISPR
  • Drug discovery
  • Computational biology
  • Cancer
  • Biology
  • Genetic screen
UN Sustainable Development Goals
  • Good health and well-being
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