reviewAnnual Review of PhysiologyNov 15, 2019BRONZE OA

Aging and Lung Disease

Cornell University · Weill Cornell Medicine

PubMed
Indexed incrossrefpubmed

Abstract

People worldwide are living longer, and it is estimated that by 2050, the proportion of the world's population over 60 years of age will nearly double. Natural lung aging is associated with molecular and physiological changes that cause alterations in lung function, diminished pulmonary remodeling and regenerative capacity, and increased susceptibility to acute and chronic lung diseases. As the aging population rapidly grows, it is essential to examine how alterations in cellular function and cell-to-cell interactions of pulmonary resident cells and systemic immune cells contribute to a higher risk of increased susceptibility to infection and development of chronic diseases, such as chronic obstructive…

Citation impact

455
total citations
FWCI
16.12
Percentile
100%
References
146
Citations per year

Authors

2

Topics & keywords

Keywords
  • Lung
  • Immune system
  • Medicine
  • Disease
  • Immunology
  • Pulmonary fibrosis
  • Population
  • Idiopathic pulmonary fibrosis
UN Sustainable Development Goals
  • Good health and well-being
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Funding